HitPredict

Interactor 1: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Interactor 2: SMC3 (P47037)
Structural maintenance of chromosomes protein 3 (DA-box protein SMC3)
Gene: SMC3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	19536198, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0016887 - ATP hydrolysis activity
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 613 Sc			1 1230
+	Sc
		510736 SSB1_YEAST (1-613): 0: 1128: 100.00		SMC1_YEAST (2-1215): 4.84e-68: 253: 16.53
+	Sc
		513208 SSB1_YEAST (1-613): 0: 1128: 100.00		SMC4_YEAST (1-1213): 6.29e-65: 244: 15.49
+	Sc
		700772 SSB2_YEAST (1-613): 0: 1118: 99.35		SMC1_YEAST (2-1215): 4.84e-68: 253: 16.53
+	Sc
		511315 SSB1_YEAST (1-613): 0: 1128: 100.00		SMC2_YEAST (1-1210): 3.6e-64: 240: 18.41
+	Sc
		769803 SSB2_YEAST (1-613): 0: 1118: 99.35		SMC4_YEAST (1-1213): 6.29e-65: 244: 15.49
+	Sc
		758744 SSB2_YEAST (1-613): 0: 1118: 99.35		SMC2_YEAST (1-1210): 3.6e-64: 240: 18.41
+	Hs
		504974 HSP7C_HUMAN (5-612): 0: 900: 59.84		SMC3_HUMAN (1-1228): 4.16e-91: 322: 30.20
+	Hs
		311464 HSP7C_HUMAN (5-612): 0: 900: 59.84		SMC2_HUMAN (1-1229): 1.89e-77: 281: 19.00
+	Hs
		504086 HSP7C_HUMAN (5-612): 0: 900: 59.84		SMC1A_HUMAN (2-1222): 6.7e-73: 268: 16.41
+	Hs
		504825 HSP7C_HUMAN (5-612): 0: 900: 59.84		SMC4_HUMAN (1-1219): 1.07e-72: 267: 17.04
+	Sc
		449985 HSP73_YEAST (9-611): 0: 677: 60.66		SMC1_YEAST (2-1215): 4.84e-68: 253: 16.53