HitPredict

Interactor 1: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Interactor 2: VPS4 (P52917)
Vacuolar protein sorting-associated protein 4 (DOA4-independent degradation protein 6) (Protein END13) (Vacuolar protein-targeting protein 10)
Gene: VPS4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0016887 - ATP hydrolysis activity
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 613 Sc			1 437
+	Sc
		768937 SSB2_YEAST (1-613): 0: 1118: 99.35		VPS4_YEAST (1-437): 9.44e-127: 375: 100.00
+	Sc
		510441 SSB1_YEAST (1-613): 0: 1128: 100.00		CDC48_YEAST (114-435): 6.42e-75: 252: 28.57
+	Sc
		511529 SSB1_YEAST (1-613): 0: 1128: 100.00		TBP6_YEAST (123-437): 1.66e-72: 244: 44.34
+	Sc
		636641 SSB2_YEAST (1-613): 0: 1118: 99.35		CDC48_YEAST (114-435): 6.42e-75: 252: 28.57
+	Sc
		511414 SSB1_YEAST (1-613): 0: 1128: 100.00		SAP1_YEAST (97-437): 3.31e-68: 234: 40.33
+	Sc
		768574 SSB2_YEAST (1-613): 0: 1118: 99.35		TBP6_YEAST (123-437): 1.66e-72: 244: 44.34
+	Hs
		260119 HSP7C_HUMAN (5-612): 0: 900: 59.84		VPS4B_HUMAN (2-436): 2.84e-118: 354: 60.50
+	Rn
		926183 HSP7C_RAT (5-612): 0: 900: 59.84		KTNA1_RAT (54-434): 1e-111: 339: 38.14
+	Hs
		503823 HSP7C_HUMAN (5-612): 0: 900: 59.84		PRS8_HUMAN (7-384): 1.05e-104: 318: 26.30
+	Hs
		503834 HSP7C_HUMAN (5-612): 0: 900: 59.84		PRS10_HUMAN (3-383): 9.3e-100: 304: 25.77
+	Hs
		503763 HSP7C_HUMAN (5-612): 0: 900: 59.84		TERA_HUMAN (114-434): 1.72e-74: 250: 29.55