HitPredict

Interactor 1: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Interactor 2: NOP3 (Q01560)
Serine/arginine (SR)-type shuttling mRNA binding protein NPL3 (Mitochondrial targeting suppressor 1 protein) (Nuclear polyadenylated RNA-binding protein 1) (Nuclear protein localization protein 3) (Polyadenylate-binding protein NPL3)
Gene: NPL3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	27001512, 19536198, 14769921
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006415 - translational termination
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 613 Sc			1 414
+	Sc
		769207 SSB2_YEAST (1-613): 0: 1118: 99.35		NOP3_YEAST (1-414): 6.5e-65: 215: 100.00
+	Sc
		510404 SSB1_YEAST (1-613): 0: 1128: 100.00		GBP2_YEAST (124-272): 1.18e-16: 83.1: 25.86
+	Sc
		633952 SSB2_YEAST (1-613): 0: 1118: 99.35		GBP2_YEAST (124-272): 1.18e-16: 83.1: 25.86
+	Sc
		376601 SSB1_YEAST (1-613): 0: 1128: 100.00		PABP_YEAST (202-285): 1.62e-11: 68: 18.39
+	Sc
		376806 SSB2_YEAST (1-613): 0: 1118: 99.35		PABP_YEAST (202-285): 1.62e-11: 68: 18.39
+	Hs
		503961 HSP7C_HUMAN (5-612): 0: 900: 59.84		SRSF1_HUMAN (117-264): 1.06e-42: 152: 26.40
+	Hs
		504019 HSP7C_HUMAN (5-612): 0: 900: 59.84		PABP4_HUMAN (190-285): 2.3e-13: 73.7: 15.15
+	Hs
		504914 HSP7C_HUMAN (5-612): 0: 900: 59.84		PUF60_HUMAN (199-352): 1.64e-12: 71.1: 13.75
+	Hs
		503332 HSP7C_HUMAN (5-612): 0: 900: 59.84		PABP1_HUMAN (190-285): 3.21e-12: 70.3: 15.15