HitPredict

Interactor 1: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Interactor 2: PKH1 (Q03407)
Serine/threonine-protein kinase PKH1 (EC 2.7.11.1) (3-phosphoinositide-dependent protein kinase 1)
Gene: PKH1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 613 Sc			1 766
+	Sc
		769313 SSB2_YEAST (1-613): 0: 1118: 99.35		PKH1_YEAST (1-766): 0: 623: 100.00
+	Sc
		412629 SSB1_YEAST (1-613): 0: 1128: 100.00		KAPA_YEAST (47-446): 5.01e-134: 404: 26.63
+	Sc
		512501 SSB1_YEAST (1-613): 0: 1128: 100.00		PKH3_YEAST (124-398): 2.34e-63: 229: 43.69
+	Sc
		769304 SSB2_YEAST (1-613): 0: 1118: 99.35		PKH3_YEAST (124-398): 2.34e-63: 229: 43.69
+	Hs
		564016 HSP76_HUMAN (3-612): 0: 901: 58.66		AKT1_HUMAN (10-454): 1.82e-144: 434: 22.22
+	Hs
		503528 HSP7C_HUMAN (5-612): 0: 900: 59.84		AKT1_HUMAN (10-454): 1.82e-144: 434: 22.22
+	Hs
		503922 HSP7C_HUMAN (5-612): 0: 900: 59.84		KPCE_HUMAN (28-460): 2.59e-139: 430: 22.22
+	Mm
		554912 HS71A_MOUSE (5-611): 0: 893: 59.44		KPCE_MOUSE (28-460): 6.97e-140: 431: 22.45
+	Hs
		254440 HSP7C_HUMAN (5-612): 0: 900: 59.84		ROCK2_HUMAN (118-580): 7.33e-123: 402: 25.11
+	Sc
		412933 SSB1_YEAST (1-613): 0: 1128: 100.00		KAPB_YEAST (119-397): 1.11e-41: 158: 32.04
+	Hs
		564201 HSP76_HUMAN (3-612): 0: 901: 58.66		KS6B2_HUMAN (119-492): 1.66e-123: 380: 28.54
+	Hs
		504896 HSP7C_HUMAN (5-612): 0: 900: 59.84		KS6B2_HUMAN (119-492): 1.66e-123: 380: 28.54
+	Sc
		412987 SSB2_YEAST (1-613): 0: 1118: 99.35		KAPB_YEAST (119-397): 1.11e-41: 158: 32.04
+	Hs
		564041 HSP76_HUMAN (3-612): 0: 901: 58.66		KS6A3_HUMAN (63-404): 2.7e-101: 330: 22.95
+	Hs
		503719 HSP7C_HUMAN (5-612): 0: 900: 59.84		KS6A3_HUMAN (63-404): 2.7e-101: 330: 22.95
+	Hs
		564080 HSP76_HUMAN (3-612): 0: 901: 58.66		KS6A1_HUMAN (125-395): 1.14e-89: 299: 28.37
+	Hs
		504119 HSP7C_HUMAN (5-612): 0: 900: 59.84		KS6A1_HUMAN (125-395): 1.14e-89: 299: 28.37
+	Hs
		182080 HSP76_HUMAN (3-612): 0: 901: 58.66		PDPK1_HUMAN (123-412): 1.77e-80: 270: 46.28
+	Hs
		182076 HSP7C_HUMAN (5-612): 0: 900: 59.84		PDPK1_HUMAN (123-412): 1.77e-80: 270: 46.28
+	Hs
		483772 HS71A_HUMAN (5-611): 0: 897: 59.93		ST38L_HUMAN (119-397): 2.34e-43: 165: 32.26