HitPredict

Interactor 1: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Interactor 2: PRP46 (Q12417)
Pre-mRNA-splicing factor PRP46 (Complexed with CEF1 protein 1) (PRP nineteen-associated complex protein 50) (PRP19-associated complex protein 50) (Pre-mRNA-processing protein 46)
Gene: PRP46

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	11805837, 19536198, 16429126
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 613 Sc			1 451
+	Sc
		769849 SSB2_YEAST (1-613): 0: 1118: 99.35		PRP46_YEAST (1-451): 2.96e-105: 321: 100.00
+	Sc
		630868 SSB2_YEAST (1-613): 0: 1118: 99.35		NLE1_YEAST (6-334): 1.12e-83: 268: 18.54
+	Sc
		511028 SSB1_YEAST (1-613): 0: 1128: 100.00		TAF5_YEAST (210-438): 2.24e-16: 83.6: 22.94
+	Sc
		512192 SSB1_YEAST (1-613): 0: 1128: 100.00		COPA_YEAST (173-435): 4.03e-16: 83.2: 24.15
+	Sc
		744626 SSB2_YEAST (1-613): 0: 1118: 99.35		TAF5_YEAST (210-438): 2.24e-16: 83.6: 22.94
+	Sc
		769053 SSB2_YEAST (1-613): 0: 1118: 99.35		COPA_YEAST (173-435): 4.03e-16: 83.2: 24.15
+	Hs
		503614 HSP7C_HUMAN (5-612): 0: 900: 59.84		LIS1_HUMAN (175-451): 4.62e-80: 255: 21.48
+	Hs
		504523 HSP7C_HUMAN (5-612): 0: 900: 59.84		FBXW7_HUMAN (6-247): 5.05e-48: 176: 16.14
+	Hs
		503817 HSP7C_HUMAN (5-612): 0: 900: 59.84		WDR5_HUMAN (4-209): 1.3e-44: 160: 15.28
+	Hs
		504344 HSP7C_HUMAN (5-612): 0: 900: 59.84		WDR5B_HUMAN (4-209): 7.06e-44: 158: 14.35
+	Hs
		503861 HSP7C_HUMAN (5-612): 0: 900: 59.84		RACK1_HUMAN (261-439): 3.85e-30: 120: 20.21
+	Hs
		564125 HSP76_HUMAN (3-612): 0: 901: 58.66		POC1A_HUMAN (4-126): 5.34e-20: 93.6: 8.59
+	Hs
		504412 HSP7C_HUMAN (5-612): 0: 900: 59.84		POC1A_HUMAN (4-126): 5.34e-20: 93.6: 8.59
+	Hs
		714020 HS71L_HUMAN (5-612): 0: 896: 59.34		POC1A_HUMAN (4-126): 5.34e-20: 93.6: 8.59
+	Hs
		209386 HSP7C_HUMAN (5-612): 0: 900: 59.84		PLRG1_HUMAN (7-167): 1.13e-17: 87.1: 10.41
+	Dm
		505116 HSP7D_DROME (5-612): 0: 884: 58.85		FBXW7_DROME (42-205): 3.25e-16: 83.3: 15.61
+	Sc
		605373 HSP74_YEAST (9-611): 0: 681: 62.15		COPA_YEAST (173-435): 4.03e-16: 83.2: 24.15
+	Sc
		450018 HSP73_YEAST (9-611): 0: 677: 60.66		TAF5_YEAST (210-438): 2.24e-16: 83.6: 22.94
+	Sc
		450129 HSP73_YEAST (9-611): 0: 677: 60.66		COPA_YEAST (173-435): 4.03e-16: 83.2: 24.15