HitPredict

Interactor 1: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Interactor 2: SMC6 (Q12749)
Structural maintenance of chromosomes protein 6 (DNA repair protein RHC18) (Rad18 homolog)
Gene: SMC6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	11805837, 33301732, 19536198
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0016887 - ATP hydrolysis activity
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 613 Sc			1 1114
+	Sc
		769900 SSB2_YEAST (1-613): 0: 1118: 99.35		SMC6_YEAST (1-1114): 1.03e-104: 357: 100.00
+	Sc
		511315 SSB1_YEAST (1-613): 0: 1128: 100.00		SMC2_YEAST (81-1099): 9.79e-59: 223: 12.13
+	Sc
		758744 SSB2_YEAST (1-613): 0: 1118: 99.35		SMC2_YEAST (81-1099): 9.79e-59: 223: 12.13
+	Sc
		769642 SSB2_YEAST (1-613): 0: 1118: 99.35		SMC5_YEAST (70-1096): 3.83e-57: 217: 12.68
+	Sc
		511836 SSB1_YEAST (1-613): 0: 1128: 100.00		SMC3_YEAST (247-1081): 1.13e-13: 78: 13.05
+	Hs
		504371 HSP7C_HUMAN (5-612): 0: 900: 59.84		SMC5_HUMAN (35-1112): 5.81e-68: 250: 13.95
+	Hs
		871656 HSP72_HUMAN (4-612): 0: 891: 59.97		SMC5_HUMAN (35-1112): 5.81e-68: 250: 13.95
+	Hs
		504825 HSP7C_HUMAN (5-612): 0: 900: 59.84		SMC4_HUMAN (5-1100): 2.66e-60: 228: 11.78
+	Hs
		311464 HSP7C_HUMAN (5-612): 0: 900: 59.84		SMC2_HUMAN (81-1099): 1.44e-52: 203: 14.02
+	Hs
		504974 HSP7C_HUMAN (5-612): 0: 900: 59.84		SMC3_HUMAN (81-1098): 8.48e-49: 191: 11.57
+	Sc
		605400 HSP74_YEAST (9-611): 0: 681: 62.15		SMC6_YEAST (1-1114): 1.03e-104: 357: 100.00