HitPredict

Interactor 1: FGF3 (P11487)
Fibroblast growth factor 3 (FGF-3) (Heparin-binding growth factor 3) (HBGF-3) (Proto-oncogene Int-2)
Gene: FGF3

Interactor 2: TMED1 (Q13445)
Transmembrane emp24 domain-containing protein 1 (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor-binding protein) (p24 family protein gamma-1) (Tp24) (p24gamma1)
Gene: TMED1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction GO:0007267 - cell-cell signaling
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 239 Hs			1 227
+	Hs
		513439 FGF3_HUMAN (13-239): 1.23e-105: 306: 100.00		TMED9_HUMAN (14-225): 3.54e-69: 213: 16.81
+	Hs
		513419 FGF3_HUMAN (13-239): 1.23e-105: 306: 100.00		TMED2_HUMAN (32-225): 3.29e-69: 212: 22.17
+	Hs
		513428 FGF3_HUMAN (13-239): 1.23e-105: 306: 100.00		TMED4_HUMAN (27-225): 4.41e-67: 208: 17.84
+	Hs
		513410 FGF3_HUMAN (13-239): 1.23e-105: 306: 100.00		TMEDA_HUMAN (31-226): 1.71e-56: 180: 19.90
+	Hs
		201502 FGF16_HUMAN (13-194): 3.11e-69: 213: 40.22		TMED7_HUMAN (25-227): 5.82e-72: 220: 33.01
+	Hs
		679699 FGF9_HUMAN (14-198): 4.02e-67: 207: 36.41		TMED7_HUMAN (25-227): 5.82e-72: 220: 33.01
+	Hs
		225928 FGF17_HUMAN (42-201): 2.04e-35: 126: 23.08		TMED1_HUMAN (16-227): 3.69e-66: 205: 100.00