HitPredict

Interactor 1: PYC (P11498)
Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB)
Gene: PC

Interactor 2: SAR1A (Q9NR31)
Small COPII coat GTPase SAR1A (EC 3.6.5.2) (COPII-associated small GTPase) (Secretion-associated Ras-related GTPase 1A)
Gene: SAR1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35844135
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1178 Hs			1 198
+	Hs
		513564 PYC_HUMAN (1-1178): 0: 1462: 100.00		ARF5_HUMAN (10-197): 4.02e-75: 225: 27.66
+	Hs
		513558 PYC_HUMAN (1-1178): 0: 1462: 100.00		ARF3_HUMAN (10-197): 2.14e-63: 195: 27.13
+	Hs
		513652 PYC_HUMAN (1-1178): 0: 1462: 100.00		SAR1B_HUMAN (1-198): 1.74e-58: 183: 89.90
+	Hs
		513539 PYC_HUMAN (1-1178): 0: 1462: 100.00		TRI23_HUMAN (27-197): 9.99e-24: 99.4: 32.75
+	Hs
		950605 ACACA_HUMAN (1-746): 1.06e-175: 573: 22.40		ARF5_HUMAN (10-197): 4.02e-75: 225: 27.66
+	Hs
		1024101 ACACA_HUMAN (1-746): 1.06e-175: 573: 22.40		SAR1A_HUMAN (1-198): 5.01e-64: 198: 100.00
+	Hs
		1024118 ACACA_HUMAN (1-746): 1.06e-175: 573: 22.40		SAR1B_HUMAN (1-198): 1.74e-58: 183: 89.90
+	Hs
		136087 ACACB_HUMAN (1-742): 5.49e-175: 572: 23.27		SAR1B_HUMAN (1-198): 1.74e-58: 183: 89.90
+	Hs
		734614 ACACA_HUMAN (1-746): 1.06e-175: 573: 22.40		TRI23_HUMAN (27-197): 9.99e-24: 99.4: 32.75
+	Hs
		135987 ACACB_HUMAN (1-742): 5.49e-175: 572: 23.27		TRI23_HUMAN (27-197): 9.99e-24: 99.4: 32.75
+	Sc
		424334 PYR1_YEAST (19-420): 2.78e-58: 223: 16.83		ARF2_YEAST (10-197): 1.56e-76: 228: 26.60
+	Hs
		653217 PYR1_HUMAN (19-420): 1.96e-55: 214: 16.07		RHOA_HUMAN (27-195): 9.13e-59: 184: 20.81
+	Hs
		398248 PCCA_HUMAN (1065-1178): 1.27e-34: 144: 30.44		ARF5_HUMAN (10-197): 4.02e-75: 225: 27.66
+	Hs
		950686 MCCA_HUMAN (1085-1178): 3.52e-27: 121: 29.00		ARF5_HUMAN (10-197): 4.02e-75: 225: 27.66
+	Hs
		398299 PCCA_HUMAN (1065-1178): 1.27e-34: 144: 30.44		SAR1A_HUMAN (1-198): 5.01e-64: 198: 100.00
+	Hs
		398316 PCCA_HUMAN (1065-1178): 1.27e-34: 144: 30.44		SAR1B_HUMAN (1-198): 1.74e-58: 183: 89.90
+	Hs
		1301284 MCCA_HUMAN (1085-1178): 3.52e-27: 121: 29.00		SAR1A_HUMAN (1-198): 5.01e-64: 198: 100.00
+	Hs
		950543 MCCA_HUMAN (1085-1178): 3.52e-27: 121: 29.00		ARF1_HUMAN (10-197): 6.12e-63: 194: 26.06
+	Hs
		398232 PCCA_HUMAN (1065-1178): 1.27e-34: 144: 30.44		TRI23_HUMAN (27-197): 9.99e-24: 99.4: 32.75
+	Hs
		734737 MCCA_HUMAN (1085-1178): 3.52e-27: 121: 29.00		TRI23_HUMAN (27-197): 9.99e-24: 99.4: 32.75