HitPredict

Interactor 1: HS90B (P11499)
Heat shock protein HSP 90-beta (Heat shock 84 kDa) (HSP 84) (HSP84) (Tumor-specific transplantation 84 kDa antigen) (TSTA)
Gene: Hsp90ab1

Interactor 2: AKT1 (P31750)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (AKT1 kinase) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha) (Thymoma viral proto-oncogene)
Gene: AKT1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 10995457
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HSP90~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
and 9 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 724
Mm

1 480
+ Bt
+ Hs
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+ Hs
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+ Hs
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024