Interactor 1: HS90B (P11499)
Heat shock protein HSP 90-beta (Heat shock 84 kDa) (HSP 84) (HSP84) (Tumor-specific transplantation 84 kDa antigen) (TSTA)
Gene: Hsp90ab1

Interactor 2: MK07 (Q9WVS8)
Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5)
Gene: Mapk7

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 23428871
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HSP90~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0043066 - negative regulation of apoptotic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 724
Mm

1 806
+ Rn
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Rn
+ Mm
+ Hs
+ At
+ Sc
+ Sc
+ Sc
+ Sc
+ Rn
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024