HitPredict

Interactor 1: AT2A2 (P11507)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: Atp2a2

Interactor 2: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32357304
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019899 - enzyme binding
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1043 Rn			1 752
+	Rn
		94131 AT2A2_RAT (1-1043): 0: 1077: 100.00		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Mm
		223146 AT2A2_MOUSE (1-1043): 0: 1075: 99.43		TAU_MOUSE (1-752): 1.92e-82: 279: 89.52
+	Hs
		496237 AT2A2_HUMAN (1-1043): 0: 1073: 98.85		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		561576 AT2A2_HUMAN (1-1043): 0: 1073: 98.85		MDC1_HUMAN (4-740): 1.03e-26: 119: 9.08
+	Rn
		416147 AT1A1_RAT (3-997): 0: 810: 26.16		TAU_RAT (1-752): 2.4e-95: 314: 100.00
+	Rn
		94112 AT1A1_RAT (3-997): 0: 810: 26.16		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Rn
		416169 AT1A3_RAT (4-997): 0: 802: 26.38		TAU_RAT (1-752): 2.4e-95: 314: 100.00
+	Rn
		94114 AT1A3_RAT (4-997): 0: 802: 26.38		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Rn
		416161 AT1A2_RAT (3-997): 0: 797: 26.07		TAU_RAT (1-752): 2.4e-95: 314: 100.00
+	Rn
		94113 AT1A2_RAT (3-997): 0: 797: 26.07		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Hs
		392995 AT1A1_HUMAN (3-997): 0: 808: 26.26		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		496196 AT1A3_HUMAN (4-997): 0: 803: 26.38		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		496589 AT1A2_HUMAN (3-997): 0: 800: 26.26		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		496323 AT2B4_HUMAN (3-1010): 0: 792: 25.79		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86