Interactor 1: CP19A (P11511)
Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen synthase)
Gene: CYP19A1

Interactor 2: CP51A (Q16850)
Lanosterol 14-alpha demethylase (LDM) (EC 1.14.14.154) (CYPLI) (Cytochrome P450 51A1) (CYP51A1) (Cytochrome P450-14DM) (Cytochrome P45014DM) (Cytochrome P450LI) (Sterol 14-alpha demethylase)
Gene: CYP51A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains p450~p450
Common GO terms GO:0005506 - iron ion binding
GO:0005789 - endoplasmic reticulum membrane
GO:0006694 - steroid biosynthetic process
GO:0016020 - membrane
GO:0016125 - sterol metabolic process
and 1 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 503
Hs

1 509
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+ Dm

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Last updated: 15 Jul 2024