HitPredict

Interactor 1: DMD (P11532)
Dystrophin
Gene: DMD

Interactor 2: ACTS (P68133)
Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
Gene: ACTA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	1544421
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Actin~CH
Common GO terms	GO:0005200 - structural constituent of cytoskeleton GO:0005829 - cytosol GO:0017022 - myosin binding GO:0030175 - filopodium
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3685 Hs			1 377
+	Hs
		809100 UTRN_HUMAN (11-2805): 1.16e-128: 459: 33.45		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Hs
		892138 DTNA_HUMAN (3092-3680): 7.11e-102: 348: 26.30		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		506816 SPTB1_HUMAN (12-522): 3.53e-54: 213: 32.57		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Dm
		284844 O77291_DROME (12-252): 1.02e-52: 209: 48.55		ACT1_DROME (1-377): 0: 604: 93.63
+	Hs
		892113 MACF1_HUMAN (1248-3142): 1.21e-46: 189: 11.89		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		932975 SPTN1_HUMAN (2427-3038): 2.94e-40: 168: 14.54		ACTS_HUMAN (1-377): 0: 605: 100.00
+	Hs
		891755 SPTN1_HUMAN (2427-3038): 2.94e-40: 168: 14.54		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		929856 SPTN1_HUMAN (2427-3038): 2.94e-40: 168: 14.54		ACTG_HUMAN (4-377): 0: 604: 93.85
+	Hs
		932145 SPTN1_HUMAN (2427-3038): 2.94e-40: 168: 14.54		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Hs
		929869 PLEC_HUMAN (187-1514): 2.33e-37: 158: 11.06		ACTG_HUMAN (4-377): 0: 604: 93.85
+	Hs
		932171 PLEC_HUMAN (187-1514): 2.33e-37: 158: 11.06		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Hs
		932157 GOGB1_HUMAN (2039-3284): 2.47e-30: 135: 9.87		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Hs
		828573 CENPF_HUMAN (2230-3220): 1.46e-24: 116: 10.50		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Hs
		891697 SPTB2_HUMAN (577-2244): 2.82e-24: 115: 10.24		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		929824 SPTB2_HUMAN (577-2244): 2.82e-24: 115: 10.24		ACTG_HUMAN (4-377): 0: 604: 93.85
+	Hs
		932107 SPTB2_HUMAN (577-2244): 2.82e-24: 115: 10.24		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Hs
		891706 DYST_HUMAN (1600-3174): 4.64e-20: 101: 9.93		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		932113 DYST_HUMAN (1600-3174): 4.64e-20: 101: 9.93		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Hs
		164588 SPTN2_HUMAN (2577-3114): 1.78e-11: 73.2: 14.73		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Mm
		930101 PLEC_MOUSE (181-844): 1.89e-12: 76.2: 10.61		ACTH_MOUSE (4-377): 0: 597: 98.40