HitPredict

Interactor 1: DMD (P11532)
Dystrophin
Gene: DMD

Interactor 2: SNTB1 (Q13884)
Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (BSYN2) (Syntrophin-2) (Tax interaction protein 43) (TIP-43)
Gene: SNTB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.706

Property	Details
Experiments	7844150, 28514442, 33961781, 8576247
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005856 - cytoskeleton GO:0016010 - dystrophin-associated glycoprotein complex GO:0032991 - protein-containing complex GO:0042383 - sarcolemma and 1 others more... GO:0045202 - synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3685 Hs			1 538
+	Mm
		513810 DMD_MOUSE (1-3685): 0: 1155: 90.37		SNTB1_MOUSE (22-538): 1.02e-158: 464: 93.81
+	Hs
		513857 DMD_HUMAN (1-3685): 0: 1187: 100.00		SNTB2_HUMAN (19-537): 3.69e-141: 420: 54.41
+	Hs
		513856 DMD_HUMAN (1-3685): 0: 1187: 100.00		SNTA1_HUMAN (15-538): 8.44e-135: 402: 47.83
+	Mm
		513793 DMD_MOUSE (1-3685): 0: 1155: 90.37		SNTB2_MOUSE (19-537): 7.83e-144: 426: 55.09
+	Mm
		513788 DMD_MOUSE (1-3685): 0: 1155: 90.37		Q3UVD6_MOUSE (15-538): 2.36e-137: 408: 48.21
+	Mm
		57227 DMD_MOUSE (1-3685): 0: 1155: 90.37		A2AKD7_MOUSE (15-538): 2.14e-137: 408: 48.21
+	Mm
		513792 DMD_MOUSE (1-3685): 0: 1155: 90.37		SNTA1_MOUSE (15-538): 7.74e-135: 402: 46.36
+	Hs
		513902 DMD_HUMAN (1-3685): 0: 1187: 100.00		SNTG1_HUMAN (104-534): 1.84e-111: 343: 22.93
+	Hs
		513904 DMD_HUMAN (1-3685): 0: 1187: 100.00		SNTG2_HUMAN (102-534): 1.57e-106: 331: 24.26
+	Mm
		513809 DMD_MOUSE (1-3685): 0: 1155: 90.37		SNTG1_MOUSE (94-534): 7.12e-111: 341: 23.50
+	Mm
		513808 DMD_MOUSE (1-3685): 0: 1155: 90.37		SNTG2_MOUSE (102-534): 3.73e-107: 332: 24.52
+	Hs
		159145 DMD_HUMAN (1-3685): 0: 1187: 100.00		CSKP_HUMAN (28-512): 1.27e-73: 253: 10.90
+	Hs
		513905 DMD_HUMAN (1-3685): 0: 1187: 100.00		PALS2_HUMAN (7-474): 7.86e-69: 232: 9.98
+	Mm
		1160362 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		SNTB1_MOUSE (22-538): 1.02e-158: 464: 93.81
+	Hs
		1046428 Q14205_HUMAN (2980-3685): 0: 651: 100.00		SNTB1_HUMAN (22-538): 6.02e-158: 462: 100.00
+	Mm
		1142421 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		SNTB2_MOUSE (19-537): 7.83e-144: 426: 55.09
+	Mm
		1113337 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		Q3UVD6_MOUSE (15-538): 2.36e-137: 408: 48.21
+	Hs
		1033832 Q14205_HUMAN (2980-3685): 0: 651: 100.00		SNTA1_HUMAN (15-538): 8.44e-135: 402: 47.83
+	Mm
		1160361 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		SNTG1_MOUSE (94-534): 7.12e-111: 341: 23.50
+	Mm
		1160360 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		SNTG2_MOUSE (102-534): 3.73e-107: 332: 24.52