HitPredict

Interactor 1: DMD (P11532)
Dystrophin
Gene: DMD

Interactor 2: DAG1 (Q14118)
Dystroglycan 1 (Dystroglycan) (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)]
Gene: DAG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.651

The method score is based on:

Property	Details
Experiments	10932245, 7592992, 19109891
Identification Methods	x-ray crystallography, affinity chromatography technology, pull down
Interaction Type	association, physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002162 - dystroglycan binding GO:0003779 - actin binding GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005886 - plasma membrane and 7 others more... GO:0008307 - structural constituent of muscle GO:0016010 - dystrophin-associated glycoprotein complex GO:0017166 - vinculin binding GO:0030175 - filopodium GO:0042383 - sarcolemma GO:0043034 - costamere GO:0045211 - postsynaptic membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	3685
Hs

1	895

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024