HitPredict

Interactor 1: DMD (P11532)
Dystrophin
Gene: DMD

Interactor 2: SNTG1 (Q9NSN8)
Gamma-1-syntrophin (G1SYN) (Syntrophin-4) (SYN4)
Gene: SNTG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.626

Property	Details
Experiments	10747910, 33961781
Identification Methods	pull down, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005634 - nucleus GO:0005856 - cytoskeleton GO:0016010 - dystrophin-associated glycoprotein complex GO:0016013 - syntrophin complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3685 Hs			1 517
+	Mm
		513809 DMD_MOUSE (1-3685): 0: 1155: 90.37		SNTG1_MOUSE (1-498): 2.44e-168: 487: 94.58
+	Hs
		513904 DMD_HUMAN (1-3685): 0: 1187: 100.00		SNTG2_HUMAN (3-501): 4.64e-143: 423: 48.94
+	Mm
		513808 DMD_MOUSE (1-3685): 0: 1155: 90.37		SNTG2_MOUSE (3-501): 1.71e-146: 432: 50.68
+	Hs
		513857 DMD_HUMAN (1-3685): 0: 1187: 100.00		SNTB2_HUMAN (26-490): 2.5e-119: 363: 22.82
+	Hs
		513860 DMD_HUMAN (1-3685): 0: 1187: 100.00		SNTB1_HUMAN (5-490): 1.51e-117: 358: 22.66
+	Hs
		513856 DMD_HUMAN (1-3685): 0: 1187: 100.00		SNTA1_HUMAN (3-490): 5.16e-115: 351: 25.30
+	Mm
		513793 DMD_MOUSE (1-3685): 0: 1155: 90.37		SNTB2_MOUSE (15-490): 2.55e-121: 367: 22.52
+	Mm
		513788 DMD_MOUSE (1-3685): 0: 1155: 90.37		Q3UVD6_MOUSE (3-490): 8.16e-119: 360: 24.75
+	Mm
		513810 DMD_MOUSE (1-3685): 0: 1155: 90.37		SNTB1_MOUSE (5-490): 1.81e-118: 360: 22.07
+	Mm
		57227 DMD_MOUSE (1-3685): 0: 1155: 90.37		A2AKD7_MOUSE (3-490): 6.58e-119: 360: 24.75
+	Mm
		513792 DMD_MOUSE (1-3685): 0: 1155: 90.37		SNTA1_MOUSE (3-490): 1.56e-117: 357: 24.55
+	Mm
		1160361 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		SNTG1_MOUSE (1-498): 2.44e-168: 487: 94.58
+	Mm
		1160360 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		SNTG2_MOUSE (3-501): 1.71e-146: 432: 50.68
+	Mm
		1142421 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		SNTB2_MOUSE (15-490): 2.55e-121: 367: 22.52
+	Mm
		1113337 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		Q3UVD6_MOUSE (3-490): 8.16e-119: 360: 24.75
+	Mm
		1160362 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		SNTB1_MOUSE (5-490): 1.81e-118: 360: 22.07
+	Hs
		1046428 Q14205_HUMAN (2980-3685): 0: 651: 100.00		SNTB1_HUMAN (5-490): 1.51e-117: 358: 22.66
+	Hs
		1033832 Q14205_HUMAN (2980-3685): 0: 651: 100.00		SNTA1_HUMAN (3-490): 5.16e-115: 351: 25.30
+	Mm
		985507 DRP2_MOUSE (2786-3680): 1.2e-152: 504: 55.18		SNTG1_MOUSE (1-498): 2.44e-168: 487: 94.58
+	Mm
		985506 DRP2_MOUSE (2786-3680): 1.2e-152: 504: 55.18		SNTG2_MOUSE (3-501): 1.71e-146: 432: 50.68