HitPredict

Interactor 1: ITBX (P11584)
Integrin beta-PS (Position-specific antigen beta subunit) (Protein myospheroid) (Protein olfactory C)
Gene: mys

Interactor 2: ITA1 (Q24247)
Integrin alpha-PS1 (Position-specific antigen subunit alpha-1) (Protein multiple edematous wings) [Cleaved into: Integrin alpha-PS1 heavy chain; Integrin alpha-PS1 light chain]
Gene: mew

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.759

The method score is based on:

Property Details
Experiments 7972082, 25294943
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF_2~Integrin_alpha2, Integrin_B_tail~Integrin_alpha2, FG-GAP~Integrin_beta, Integrin_alpha2~Integrin_beta
Common GO terms GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0007015 - actin filament organization
GO:0007157 - heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
and 17 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 846
Dm

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024