HitPredict

Interactor 1: NHP6B (P11633)
Non-histone chromosomal protein 6B
Gene: NHP6B

Interactor 2: TUP1 (P16649)
General transcriptional corepressor TUP1 (Flocculation suppressor protein) (Glucose repression regulatory protein TUP1) (Repressor AER2)
Gene: TUP1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.609

Property	Details
Experiments	11095729, 11525400
Identification Methods	pull down, protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 99 Sc			1 713
+	Hs
		196970 SOX2_HUMAN (20-98): 1.91e-30: 111: 26.58		PRP4_HUMAN (336-603): 3.34e-64: 223: 23.25
+	Hs
		197008 SSRP1_HUMAN (3-99): 1.61e-27: 106: 32.99		PRP4_HUMAN (336-603): 3.34e-64: 223: 23.25
+	Hs
		817979 SOX2_HUMAN (20-98): 1.91e-30: 111: 26.58		TBL3_HUMAN (303-705): 2.41e-50: 190: 17.11
+	Hs
		818441 SOX2_HUMAN (20-98): 1.91e-30: 111: 26.58		TBL1R_HUMAN (480-712): 5.93e-52: 190: 21.07
+	Mm
		1142008 Q60I23_MOUSE (2-98): 2.96e-30: 110: 21.65		TBL1R_MOUSE (464-712): 1.88e-51: 188: 21.28
+	Hs
		996881 SSRP1_HUMAN (3-99): 1.61e-27: 106: 32.99		TBL1R_HUMAN (480-712): 5.93e-52: 190: 21.07
+	Hs
		996930 SSRP1_HUMAN (3-99): 1.61e-27: 106: 32.99		NLE1_HUMAN (553-712): 2.91e-36: 144: 26.09
+	Ce
		1089274 SOX2_CAEEL (7-98): 9.1e-33: 116: 25.00		WDR51_CAEEL (89-470): 2.04e-31: 128: 12.47
+	Hs
		996824 SSRP1_HUMAN (3-99): 1.61e-27: 106: 32.99		SNR40_HUMAN (562-710): 2.51e-32: 130: 24.83
+	Hs
		996813 SSRP1_HUMAN (3-99): 1.61e-27: 106: 32.99		FBXW7_HUMAN (551-708): 1.98e-30: 129: 26.42
+	Hs
		1281404 HM20A_HUMAN (3-99): 3.62e-27: 103: 36.08		FBXW7_HUMAN (551-708): 1.98e-30: 129: 26.42
+	Hs
		245636 SOX17_HUMAN (1-98): 1.57e-30: 113: 25.51		TBL1X_HUMAN (556-711): 2.78e-22: 103: 20.63
+	Hs
		245575 SOX2_HUMAN (20-98): 1.91e-30: 111: 26.58		TBL1X_HUMAN (556-711): 2.78e-22: 103: 20.63
+	Hs
		245570 SOX6_HUMAN (3-98): 5.3e-28: 107: 22.92		TBL1X_HUMAN (556-711): 2.78e-22: 103: 20.63
+	Hs
		245569 SOX5_HUMAN (2-98): 1.38e-27: 106: 24.74		TBL1X_HUMAN (556-711): 2.78e-22: 103: 20.63
+	Hs
		245594 SSRP1_HUMAN (3-99): 1.61e-27: 106: 32.99		TBL1X_HUMAN (556-711): 2.78e-22: 103: 20.63
+	Hs
		817868 SOX2_HUMAN (20-98): 1.91e-30: 111: 26.58		WDR5_HUMAN (606-712): 3.54e-21: 97.1: 21.50
+	Hs
		903169 SSRP1_HUMAN (3-99): 1.61e-27: 106: 32.99		WDR5_HUMAN (606-712): 3.54e-21: 97.1: 21.50
+	Hs
		903450 CIC_HUMAN (1-96): 9.84e-28: 106: 25.00		WDR5_HUMAN (606-712): 3.54e-21: 97.1: 21.50
+	Hs
		1074805 CIC_HUMAN (1-96): 9.84e-28: 106: 25.00		TAF5_HUMAN (446-513): 3.47e-10: 65.5: 48.53