HitPredict

Interactor 1: NHP6B (P11633)
Non-histone chromosomal protein 6B
Gene: NHP6B

Interactor 2: ISW2 (Q08773)
ISWI chromatin-remodeling complex ATPase ISW2 (EC 3.6.4.-) (Imitation switch protein 2)
Gene: ISW2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.588

Property	Details
Experiments	11805826, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 99 Sc			1 1120
+	Mm
		1142014 Q60I23_MOUSE (2-98): 2.96e-30: 110: 21.65		SMCA5_MOUSE (55-1089): 0: 957: 47.63
+	Hs
		229339 SOX2_HUMAN (20-98): 1.91e-30: 111: 26.58		SMCA5_HUMAN (55-1089): 0: 954: 47.44
+	Hs
		817986 SOX2_HUMAN (20-98): 1.91e-30: 111: 26.58		CHD3_HUMAN (25-1114): 0: 823: 26.91
+	Hs
		727856 SOX6_HUMAN (3-98): 5.3e-28: 107: 22.92		CHD3_HUMAN (25-1114): 0: 823: 26.91
+	Hs
		1332326 SOX17_HUMAN (1-98): 1.57e-30: 113: 25.51		CHD7_HUMAN (9-1110): 0: 814: 25.52
+	Hs
		1311936 SOX7_HUMAN (9-98): 3.59e-30: 111: 25.56		CHD7_HUMAN (9-1110): 0: 814: 25.52
+	Hs
		818550 SOX2_HUMAN (20-98): 1.91e-30: 111: 26.58		CHD7_HUMAN (9-1110): 0: 814: 25.52
+	Mm
		57186 Q60I23_MOUSE (2-98): 2.96e-30: 110: 21.65		CHD7_MOUSE (9-1110): 0: 812: 25.43
+	Hs
		818056 SOX2_HUMAN (20-98): 1.91e-30: 111: 26.58		CHD4_HUMAN (31-1119): 0: 803: 27.38
+	Hs
		818484 SOX2_HUMAN (20-98): 1.91e-30: 111: 26.58		CHD8_HUMAN (6-1093): 0: 799: 25.28
+	Mm
		1142004 Q60I23_MOUSE (2-98): 2.96e-30: 110: 21.65		CHD4_MOUSE (31-1002): 0: 799: 29.87
+	Mm
		818727 SOX2_MOUSE (2-98): 6.69e-30: 109: 21.65		CHD4_MOUSE (31-1002): 0: 799: 29.87
+	Hs
		818279 SOX2_HUMAN (20-98): 1.91e-30: 111: 26.58		CHD6_HUMAN (2-1118): 0: 784: 26.16
+	Hs
		818102 SOX2_HUMAN (20-98): 1.91e-30: 111: 26.58		CHD9_HUMAN (5-1119): 0: 782: 25.55
+	Hs
		817810 SOX2_HUMAN (20-98): 1.91e-30: 111: 26.58		SMCA4_HUMAN (115-892): 0: 681: 30.39
+	Hs
		847069 SOX7_HUMAN (9-98): 3.59e-30: 111: 25.56		SMCA4_HUMAN (115-892): 0: 681: 30.39
+	Hs
		846868 SOX17_HUMAN (1-98): 1.57e-30: 113: 25.51		SMCA2_HUMAN (172-649): 4.23e-124: 418: 44.73
+	Hs
		817809 SOX2_HUMAN (20-98): 1.91e-30: 111: 26.58		SMCA2_HUMAN (172-649): 4.23e-124: 418: 44.73
+	Hs
		846863 SOX7_HUMAN (9-98): 3.59e-30: 111: 25.56		SMCA2_HUMAN (172-649): 4.23e-124: 418: 44.73
+	Mm
		818702 SOX2_MOUSE (2-98): 6.69e-30: 109: 21.65		SMCA4_MOUSE (172-649): 2.84e-124: 419: 45.33