HitPredict

Interactor 1: K2C8 (P11679)
Keratin, type II cytoskeletal 8 (Cytokeratin endo A) (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Type-II keratin Kb8)
Gene: Krt8

Interactor 2: CFTR (P26361)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	22038833
Identification Methods	surface plasmon resonance
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 490 Mm			1 1476
+	Hs
		444525 K2C7_HUMAN (14-408): 4.1e-145: 425: 67.00		CFTR_HUMAN (1-1476): 0: 1075: 78.33
+	Hs
		529780 KRT84_HUMAN (2-426): 7.96e-97: 305: 56.47		CFTR_HUMAN (1-1476): 0: 1075: 78.33
+	Hs
		529119 KRT81_HUMAN (5-424): 1.11e-89: 284: 49.88		CFTR_HUMAN (1-1476): 0: 1075: 78.33
+	Hs
		213928 KRT86_HUMAN (12-424): 1.63e-88: 280: 50.70		CFTR_HUMAN (1-1476): 0: 1075: 78.33
+	Hs
		528963 KRT85_HUMAN (5-436): 8.09e-88: 279: 50.69		CFTR_HUMAN (1-1476): 0: 1075: 78.33
+	Hs
		318772 K2C75_HUMAN (2-411): 1.14e-77: 254: 59.39		CFTR_HUMAN (1-1476): 0: 1075: 78.33
+	Hs
		529130 K2C72_HUMAN (10-411): 2.85e-71: 237: 56.62		CFTR_HUMAN (1-1476): 0: 1075: 78.33
+	Hs
		380440 K2C6B_HUMAN (62-411): 1.64e-66: 225: 68.75		CFTR_HUMAN (1-1476): 0: 1075: 78.33
+	Hs
		528450 K2C5_HUMAN (62-411): 4.56e-66: 225: 69.60		CFTR_HUMAN (1-1476): 0: 1075: 78.33
+	Hs
		528760 K2C6C_HUMAN (62-411): 1.88e-66: 225: 69.03		CFTR_HUMAN (1-1476): 0: 1075: 78.33
+	Hs
		529332 K2C74_HUMAN (6-471): 7.63e-67: 225: 48.72		CFTR_HUMAN (1-1476): 0: 1075: 78.33
+	Hs
		359458 K2C6A_HUMAN (62-411): 6.35e-65: 221: 69.03		CFTR_HUMAN (1-1476): 0: 1075: 78.33
+	Hs
		529503 KRT35_HUMAN (8-408): 9.98e-66: 220: 26.37		CFTR_HUMAN (1-1476): 0: 1075: 78.33
+	Hs
		408988 K2C8_HUMAN (1-490): 6.52e-61: 208: 86.53		CFTR_HUMAN (1-1476): 0: 1075: 78.33