Interactor 1: CP2C9 (P11712)
Cytochrome P450 2C9 (EC 1.14.14.1) ((R)-limonene 6-monooxygenase) (EC 1.14.14.53) ((S)-limonene 6-monooxygenase) (EC 1.14.14.51) ((S)-limonene 7-monooxygenase) (EC 1.14.14.52) (CYPIIC9) (Cholesterol 25-hydroxylase) (Cytochrome P-450MP) (Cytochrome P450 MP-4) (Cytochrome P450 MP-8) (Cytochrome P450 PB-1) (S-mephenytoin 4-hydroxylase)
Gene: CYP2C9

Interactor 2: CP2CI (P33260)
Cytochrome P450 2C18 (EC 1.14.14.1) (CYPIIC18) (Cytochrome P450-6b/29c)
Gene: CYP2C18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains p450~p450
Common GO terms GO:0004497 - monooxygenase activity
GO:0005506 - iron ion binding
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
and 7 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 490
Hs

1 490
+ Hs
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+ Hs
+ Oc
+ Hs
+ Hs
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+ Hs
+ Hs

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Last updated: 15 Jul 2024