HitPredict

Interactor 1: MPRI (P11717)
Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222)
Gene: IGF2R

Interactor 2: MPRI (P11717)
Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222)
Gene: IGF2R

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 22681933
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CIMR~CIMR, CIMR~fn2, fn2~fn2
Common GO terms GO:0000139 - Golgi membrane
GO:0001889 - liver development
GO:0001965 - G-protein alpha-subunit binding
GO:0001972 - retinoic acid binding
GO:0005010 - insulin-like growth factor receptor activity
and 38 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 2491
Hs

1 2491
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Last updated: 15 Jul 2024