Interactor 1: MPRI (P11717)
Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222)
Gene: IGF2R

Interactor 2: GGA1 (Q9UJY5)
ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1)
Gene: GGA1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.754

The method score is based on:

Property Details
Experiments 11859376, 15117318, 11390366, 14567678, 12060753, 11859375, 11387475, 20676133, unassigned3573
Identification Methods two hybrid, x-ray crystallography, pull down, affinity chromatography technology, far western blotting, fluorescence polarization spectroscopy
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005769 - early endosome
GO:0005794 - Golgi apparatus
GO:0005802 - trans-Golgi network
GO:0010008 - endosome membrane
GO:0016020 - membrane
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 2491
Hs

1 639
+ Hs
+ Hs
+ Mm
+ Bt
+ Bt
+ Bt
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024