Interactor 1: ADHX (P11766)
Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase 5) (Alcohol dehydrogenase class chi chain) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutathione dehydrogenase) (EC 1.1.1.284)
Gene: ADH5

Interactor 2: ADHX (P11766)
Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase 5) (Alcohol dehydrogenase class chi chain) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutathione dehydrogenase) (EC 1.1.1.284)
Gene: ADH5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.744

The method score is based on:

Property Details
Experiments 12484756, 21988832
Identification Methods x-ray crystallography, two hybrid
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ADH_N~ADH_N, ADH_N~ADH_zinc_N, ADH_zinc_N~ADH_zinc_N
Common GO terms GO:0001523 - retinoid metabolic process
GO:0003016 - respiratory system process
GO:0004024 - alcohol dehydrogenase (NAD+) activity, zinc-dependent
GO:0005504 - fatty acid binding
GO:0005739 - mitochondrion
and 14 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 374
Hs

1 374
+ At
+ Hs
+ Hs
+ Hs
+ At
+ Ec
+ Ce
+ Sc
+ Hs
+ Hs
+ Ce
+ Ph
+ Sc
+ Dm
+ Sc

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Last updated: 15 Jul 2024