HitPredict

Interactor 1: CDK4 (P11802)
Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)
Gene: CDK4

Interactor 2: MARCS (P29966)
Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL)
Gene: MARCKS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10359664
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 303 Hs			1 332
+	Hs
		625147 CDK2_HUMAN (3-301): 5.33e-145: 411: 44.22		MARCS_HUMAN (1-322): 2.14e-23: 100: 100.00
+	Hs
		414761 CDK1_HUMAN (3-300): 8.98e-130: 372: 42.24		MARCS_HUMAN (1-322): 2.14e-23: 100: 100.00
+	Hs
		625528 CDK2_HUMAN (3-301): 5.33e-145: 411: 44.22		TITIN_HUMAN (1-308): 6.95e-09: 59.4: 10.71
+	Mm
		581220 CDK5_MOUSE (3-301): 6.95e-124: 357: 43.09		NFH_MOUSE (2-327): 6.57e-11: 65.6: 15.90
+	Rn
		974742 CDK5_RAT (3-301): 2.58e-123: 356: 43.42		SYNJ1_RAT (2-330): 4.78e-09: 59.8: 10.09
+	Dm
		820723 CDK5_DROME (5-295): 8.98e-69: 217: 42.23		CPN_DROME (34-331): 7.5e-09: 59: 13.29