Interactor 1: CDK4 (P11802)
Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)
Gene: CDK4
Interactor 2: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 0.60 | 0.770 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28042499, 8805225, 15065884, 10022865, 28218424, 28205554, 10580009, 35271311, 9529249, 10585280, 17881001, 11900540, 10491434, 11556834, 17909018, 15232106, 26186194, 26496610, 28514442, 17353931 and 12 others
more... |
| Identification Methods | affinity chromatography technology, unspecified method, pull down, fluorescent resonance energy transfer, two hybrid, enzymatic study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification, protein array |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0051726 - regulation of cell cycle |
| Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
