Interactor 1: CDK4 (P11802)
Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)
Gene: CDK4

Interactor 2: CDN2B (P42772)
Cyclin-dependent kinase 4 inhibitor B (Multiple tumor suppressor 2) (MTS-2) (p14-INK4b) (p15-INK4b) (p15INK4B)
Gene: CDKN2B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.991

The method score is based on:

Property Details
Experiments 10022865, 28205554, 24981860, 26186194, 16189514, 26496610, 25910212, 28514442, 16169070, 32296183, 33961781, 32707033, 21900206, 19447967, 23602568, 23455922, 31515488, unassigned1304
Identification Methods pull down, fluorescent resonance energy transfer, affinity chromatography technology, two hybrid, two hybrid array, two hybrid prey pooling approach, bimolecular fluorescence complementation, anti tag coimmunoprecipitation, split luciferase complementation, two hybrid bait and prey pooling approach and 3 others

more...

Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 303
Hs

1 138
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Last updated: 15 Jul 2024