Interactor 1: CDK4 (P11802)
Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)
Gene: CDK4
Interactor 2: CDN2C (P42773)
Cyclin-dependent kinase 4 inhibitor C (Cyclin-dependent kinase 6 inhibitor) (p18-INK4c) (p18-INK6)
Gene: CDKN2C
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.992 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 17353931, 27107012, 10022865, 28205554, 32296183, 8001816, 33961781, 25416956, 26186194, 25910212, 24981860, 35271311, 32707033, 11900540, 21988832, 23602568, 23455922, 31515488, unassigned1304 |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, fluorescent resonance energy transfer, anti bait coimmunoprecipitation, barcode fusion genetics two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach, validated two hybrid and 3 others
more... |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ank_2~Pkinase, Ank_4~Pkinase |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol |
| Homologous interactions | 17 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
