Interactor 1: CDK4 (P11802)
Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)
Gene: CDK4
Interactor 2: CDN2D (P55273)
Cyclin-dependent kinase 4 inhibitor D (p19-INK4d)
Gene: CDKN2D
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.988 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27107012, 10022865, 32296183, 24981860, 33961781, 23718855, 25416956, 26186194, 16189514, 25910212, 28514442, 32707033, 23602568, 31515488, unassigned1304 |
| Identification Methods | two hybrid, pull down, affinity chromatography technology, validated two hybrid, barcode fusion genetics two hybrid, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation, split luciferase complementation, two hybrid bait and prey pooling approach and 2 others
more... |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ank~Pkinase, Ank_2~Pkinase |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0097129 - cyclin D2-CDK4 complex |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
