Interactor 1: CDK4 (P11802)
Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)
Gene: CDK4

Interactor 2: FOXM1 (Q08050)
Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HFH-11) (HNF-3/fork-head homolog 11) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident) (Winged-helix factor from INS-1 cells)
Gene: FOXM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 0.60 0.569

The method score is based on:

Property Details
Experiments 22094256
Identification Methods enzymatic study, protein kinase assay
Interaction Type direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008284 - positive regulation of cell population proliferation
GO:0051726 - regulation of cell cycle
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 303
Hs

1 763
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024