Interactor 1: SRF (P11831)
Serum response factor (SRF)
Gene: SRF

Interactor 2: ELK4 (P28324)
ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1) (SRF accessory protein 1)
Gene: ELK4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 0.60 0.637

The method score is based on:

Property Details
Experiments 11406578, 9271374, 7854423
Identification Methods x-ray crystallography, two hybrid
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
and 4 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 508
Hs

1 431
+ Rn
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs

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Last updated: 15 Jul 2024