HitPredict

Interactor 1: SRF (P11831)
Serum response factor (SRF)
Gene: SRF

Interactor 2: PRKDC (P78527)
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)
Gene: PRKDC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 0.60 0.619

The method score is based on:

Property Details
Experiments 35016035, 8407951
Identification Methods affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0007507 - heart development
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 1 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 508
Hs

1 4128
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024