HitPredict

Interactor 1: SRF (P11831)
Serum response factor (SRF)
Gene: SRF

Interactor 2: MRTFB (Q9ULH7)
Myocardin-related transcription factor B (MRTF-B) (MKL/myocardin-like protein 2) (Megakaryoblastic leukemia 2)
Gene: MRTFB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.612

Property	Details
Experiments	14565952, 12397177
Identification Methods	affinity chromatography technology, affinity technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II GO:1902895 - positive regulation of miRNA transcription
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 508 Hs			1 1088
+	Rn
		88620 D3ZHH8_RAT (1-508): 7.79e-128: 383: 96.06		F1LV40_RAT (197-1088): 1.38e-17: 90.6: 16.01
+	Hs
		515614 SRF_HUMAN (1-508): 1.08e-122: 370: 100.00		MRTFA_HUMAN (207-1088): 3.88e-16: 85.9: 13.75
+	Hs
		515606 SRF_HUMAN (1-508): 1.08e-122: 370: 100.00		MYCD_HUMAN (312-1085): 2.59e-11: 70.1: 12.85
+	Hs
		515592 SRF_HUMAN (1-508): 1.08e-122: 370: 100.00		NCOA6_HUMAN (110-1067): 3.09e-09: 63.6: 8.12
+	Mm
		1257680 SRF_MOUSE (1-508): 5.21e-111: 340: 95.87		MYCD_MOUSE (319-1085): 2.46e-11: 70.1: 10.64