HitPredict

Interactor 1: ITB2 (P11835)
Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18)
Gene: Itgb2

Interactor 2: PLEC (Q9QXS1)
Plectin (PCN) (PLTN) (Plectin-1) (Plectin-6)
Gene: PLEC

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	30333137
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005925 - focal adhesion
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 771 Mm			1 4691
+	Mm
		447132 ITB1_MOUSE (9-768): 0: 680: 45.13		PLEC_MOUSE (1-4691): 0: 1786: 100.00
+	Mm
		222586 ITB3_MOUSE (22-768): 0: 616: 38.99		PLEC_MOUSE (1-4691): 0: 1786: 100.00
+	Hs
		556444 ITB4_HUMAN (1-758): 0: 577: 31.59		PLEC_HUMAN (1-4691): 0: 1743: 93.40
+	Hs
		403752 ITB1_HUMAN (8-768): 0: 681: 45.20		ACTN1_HUMAN (163-895): 3.91e-109: 375: 24.48
+	Gg
		396530 ITB1_CHICK (11-768): 0: 671: 46.21		ACTN1_CHICK (160-895): 4.81e-107: 368: 24.51
+	Mm
		515654 ITB2_MOUSE (1-771): 0: 706: 100.00		SPTB2_MOUSE (1398-3172): 3.34e-19: 98.9: 10.58
+	Mm
		222535 ITB3_MOUSE (22-768): 0: 616: 38.99		SPTB2_MOUSE (1398-3172): 3.34e-19: 98.9: 10.58
+	Hs
		556435 ITB4_HUMAN (1-758): 0: 577: 31.59		DYST_HUMAN (4193-4603): 9.26e-20: 101: 19.22
+	Dm
		246721 TENM_DROME (502-723): 2.73e-36: 150: 18.78		ACTN_DROME (183-902): 3.2e-119: 405: 23.46
+	Hs
		1356681 TEN1_HUMAN (331-621): 3.36e-33: 140: 17.50		MACF1_HUMAN (4281-4623): 2.12e-35: 152: 18.95
+	Dm
		54279 TENM_DROME (502-723): 2.73e-36: 150: 18.78		A1Z9J0_DROME (457-1880): 6.8e-18: 94.7: 9.54
+	Dm
		54284 TENM_DROME (502-723): 2.73e-36: 150: 18.78		A1Z9J1_DROME (471-1132): 1.73e-09: 66.9: 10.74
+	Dm
		54273 NOTCH_DROME (355-640): 8.23e-14: 77.8: 12.90		A1Z9I9_DROME (471-1146): 3.51e-09: 65.8: 9.84