Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: PAN3 (Q58A45)
PAN2-PAN3 deadenylation complex subunit PAN3 (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 3) (PAN deadenylation complex subunit 3)
Gene: PAN3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.739

The method score is based on:

Property Details
Experiments 23340509, 18056425, 31104843, 29395067, 17785442, 17595167
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, proximity labelling technology, anti tag coimmunoprecipitation, isothermal titration calorimetry, nuclear magnetic resonance
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0008143 - poly(A) binding
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 636
Hs

1 887
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024