HitPredict

Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: RENT1 (Q92900)
Regulator of nonsense transcripts 1 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1)
Gene: UPF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.736

The method score is based on:

Property Details
Experiments 29395067, 12723973, 35271311, 19417104, 21145460, 23665581
Identification Methods proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 636
Hs

1 1129
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024