Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1
Interactor 2: ATX2 (Q99700)
Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein)
Gene: ATXN2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.87 | 1.00 | 0.936 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29395067, 15663938, 24981860, 20181956, 32814053 |
| Identification Methods | proximity labelling technology, two hybrid, affinity chromatography technology, x-ray crystallography, pull down, two hybrid array, two hybrid pooling approach, validated two hybrid, surface plasmon resonance, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PABP~PAM2 |
| Common GO terms | GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0010494 - cytoplasmic stress granule and 2 others more... |
| Homologous interactions | 13 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
