HitPredict

Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: MKRN1 (Q9UHC7)
E3 ubiquitin-protein ligase makorin-1 (EC 2.3.2.27) (RING finger protein 61) (RING-type E3 ubiquitin transferase makorin-1)
Gene: MKRN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.670

Property	Details
Experiments	31640799, 26265008, 32460013
Identification Methods	affinity chromatography technology, enzymatic study, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 482
+	Hs
		1031488 PABP4_HUMAN (1-635): 0: 534: 74.69		MKRN1_HUMAN (31-482): 0: 556: 100.00
+	Hs
		516487 PABP1_HUMAN (1-636): 0: 582: 100.00		MKRN3_HUMAN (13-482): 1.84e-168: 486: 51.13
+	Hs
		1023561 PABP3_HUMAN (1-636): 0: 541: 91.37		MKRN3_HUMAN (13-482): 1.84e-168: 486: 51.13
+	Hs
		516684 PABP1_HUMAN (1-636): 0: 582: 100.00		MKRN2_HUMAN (56-451): 9.27e-154: 445: 45.34
+	Hs
		1023456 PABP4_HUMAN (1-635): 0: 534: 74.69		MKRN3_HUMAN (13-482): 1.84e-168: 486: 51.13
+	Hs
		1031454 PABP4_HUMAN (1-635): 0: 534: 74.69		MKRN2_HUMAN (56-451): 9.27e-154: 445: 45.34
+	Hs
		1288644 PABP5_HUMAN (6-179): 5.04e-39: 149: 25.26		MKRN1_HUMAN (31-482): 0: 556: 100.00
+	Hs
		1288624 PABP5_HUMAN (6-179): 5.04e-39: 149: 25.26		MKRN2_HUMAN (56-451): 9.27e-154: 445: 45.34
+	Dm
		597087 PABP_DROME (2-448): 6.58e-63: 221: 25.21		Q9VP20_DROME (58-427): 3.9e-113: 340: 35.03