Interactor 1: DLDH1 (P11959)
Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (E3 component of pyruvate complex)
Gene: pdhD

Interactor 2: ODP2 (P11961)
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (E2)
Gene: pdhC

Species: Geobacillus stearothermophilus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.800

The method score is based on:

Property Details
Experiments 8805537, 18184587
Identification Methods x-ray crystallography, 3D electron microscopy, molecular sieving
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains E3_binding~Pyr_redox_2, E3_binding~Pyr_redox_dim
Common GO terms GO:0005737 - cytoplasm
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 470
Gs

1 428
+ Hs
+ Hs
+ Dm
+ Hs
+ Sc
+ Ec
+ Sc
+ At
+ Ss
+ At
+ Hs
+ Ec

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024