Interactor 1: SIR4 (P11978)
Regulatory protein SIR4 (Silent information regulator 4)
Gene: SIR4

Interactor 2: KU70 (P32807)
ATP-dependent DNA helicase II subunit 1 (EC 3.6.4.12) (ATP-dependent DNA helicase II subunit Ku70) (High affinity DNA-binding factor subunit 1)
Gene: YKU70

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 0.60 0.691

The method score is based on:

Property Details
Experiments 9278054, 24567323, 18791224, 21822217
Identification Methods two hybrid, affinity chromatography technology
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0003690 - double-stranded DNA binding
GO:0006303 - double-strand break repair via nonhomologous end joining
GO:0030466 - silent mating-type cassette heterochromatin formation
GO:0031509 - subtelomeric heterochromatin formation
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1358
Sc

1 602
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024