HitPredict

Interactor 1: TCPA (P11983)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1A) (TCP-1-A) (Tailless complex polypeptide 1B) (TCP-1-B)
Gene: Tcp1

Interactor 2: HDAC4 (Q6NZM9)
Histone deacetylase 4 (HD4) (EC 3.5.1.98)
Gene: HDAC4

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	31040226
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 556 Mm			1 1076
+	Mm
		945965 TCPE_MOUSE (4-532): 0: 609: 31.84		HDAC4_MOUSE (1-1065): 0: 837: 100.00
+	Mm
		945920 TCPH_MOUSE (1-551): 0: 572: 34.64		HDAC4_MOUSE (1-1065): 0: 837: 100.00
+	Hs
		573531 TCPA_HUMAN (1-556): 0: 628: 96.40		HDAC5_HUMAN (1-1076): 0: 658: 54.49
+	Hs
		826942 TCPG_HUMAN (5-555): 0: 588: 32.49		HDAC5_HUMAN (1-1076): 0: 658: 54.49
+	Hs
		1306741 TCPH_HUMAN (1-543): 0: 559: 34.06		HDAC5_HUMAN (1-1076): 0: 658: 54.49
+	Hs
		573251 TCPA_HUMAN (1-556): 0: 628: 96.40		HDAC1_HUMAN (643-1040): 1.94e-162: 490: 24.03
+	Hs
		573401 TCPA_HUMAN (1-556): 0: 628: 96.40		HDAC2_HUMAN (664-1074): 1.17e-160: 485: 22.84
+	Hs
		177188 TCPA_HUMAN (1-556): 0: 628: 96.40		HDAC3_HUMAN (647-1073): 3.57e-153: 464: 20.77
+	Hs
		826651 TCPG_HUMAN (5-555): 0: 588: 32.49		HDAC1_HUMAN (643-1040): 1.94e-162: 490: 24.03
+	Hs
		826803 TCPG_HUMAN (5-555): 0: 588: 32.49		HDAC2_HUMAN (664-1074): 1.17e-160: 485: 22.84
+	Hs
		177233 TCPG_HUMAN (5-555): 0: 588: 32.49		HDAC3_HUMAN (647-1073): 3.57e-153: 464: 20.77
+	Hs
		1038670 TCPH_HUMAN (1-543): 0: 559: 34.06		HDAC1_HUMAN (643-1040): 1.94e-162: 490: 24.03
+	Hs
		177367 TCPH_HUMAN (1-543): 0: 559: 34.06		HDAC3_HUMAN (647-1073): 3.57e-153: 464: 20.77
+	Sc
		519912 TCPA_YEAST (4-543): 0: 556: 61.17		RPD3_YEAST (634-1067): 6.98e-154: 466: 21.98
+	Hs
		573514 TCPA_HUMAN (1-556): 0: 628: 96.40		HDAC6_HUMAN (644-1033): 2.57e-111: 376: 36.74
+	Hs
		826927 TCPG_HUMAN (5-555): 0: 588: 32.49		HDAC6_HUMAN (644-1033): 2.57e-111: 376: 36.74
+	Hs
		1306720 TCPH_HUMAN (1-543): 0: 559: 34.06		HDAC6_HUMAN (644-1033): 2.57e-111: 376: 36.74
+	Sp
		140519 TCPG_SCHPO (1-539): 0: 568: 29.89		PHD1_SCHPO (670-1000): 1.11e-23: 107: 29.11
+	Sp
		140556 TCPA_SCHPO (2-545): 0: 561: 64.42		PHD1_SCHPO (670-1000): 1.11e-23: 107: 29.11
+	Sc
		519976 TCPA_YEAST (4-543): 0: 556: 61.17		HOS2_YEAST (633-950): 4.69e-24: 108: 28.09