HitPredict

Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA

Interactor 2: CCNO (P22674)
Cyclin-O
Gene: CCNO

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	12171929, 10393198
Identification Methods	affinity chromatography technology, two hybrid, fluorescence microscopy, coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0005634 - nucleus GO:0005813 - centrosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 261 Hs			1 350
+	Hs
		517031 PCNA_HUMAN (1-261): 1.04e-125: 359: 100.00		CCNB1_HUMAN (2-346): 1.61e-100: 305: 19.39
+	Hs
		517044 PCNA_HUMAN (1-261): 1.04e-125: 359: 100.00		CCNA2_HUMAN (2-345): 1.71e-96: 294: 23.92
+	Hs
		331628 PCNA_HUMAN (1-261): 1.04e-125: 359: 100.00		CCNE2_HUMAN (4-289): 4.08e-86: 267: 22.15
+	Hs
		517059 PCNA_HUMAN (1-261): 1.04e-125: 359: 100.00		CCNE1_HUMAN (15-324): 3.7e-84: 262: 18.50