HitPredict

Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA

Interactor 2: CCNE1 (P24864)
G1/S-specific cyclin-E1
Gene: CCNE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005813 - centrosome
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 261 Hs			1 410
+	Hs
		517044 PCNA_HUMAN (1-261): 1.04e-125: 359: 100.00		CCNA2_HUMAN (2-369): 1.62e-99: 304: 20.58
+	Hs
		331628 PCNA_HUMAN (1-261): 1.04e-125: 359: 100.00		CCNE2_HUMAN (4-402): 7.36e-97: 297: 47.38
+	Hs
		517031 PCNA_HUMAN (1-261): 1.04e-125: 359: 100.00		CCNB1_HUMAN (1-365): 5.55e-95: 293: 18.82