Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA

Interactor 2: RFC5 (P40937)
Replication factor C subunit 5 (Activator 1 36 kDa subunit) (A1 36 kDa subunit) (Activator 1 subunit 5) (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36)
Gene: RFC5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.882

The method score is based on:

Property Details
Experiments 8999859, 9228079, 12171929, 24958773
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~PCNA_C, AAA~PCNA_N
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0019899 - enzyme binding
GO:1900264 - positive regulation of DNA-directed DNA polymerase activity
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 261
Hs

1 340
+ Hs
+ Bt
+ Dm
+ Hs
+ Bt
+ Dm
+ Dm
+ Hs
+ Sc
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024