HitPredict

Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA

Interactor 2: CDN1C (P49918)
Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57Kip2)
Gene: CDKN1C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	9465025, 22634751
Identification Methods	two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0044877 - protein-containing complex binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 261 Hs			1 316
+	Mm
		572239 PCNA_MOUSE (1-261): 1.25e-125: 358: 96.94		CDN1A_MOUSE (16-155): 5.85e-33: 121: 27.78
+	Hs
		517110 PCNA_HUMAN (1-261): 1.04e-125: 359: 100.00		CDN1A_HUMAN (17-148): 7.59e-31: 115: 29.20
+	Hs
		758259 Q6FI35_HUMAN (1-261): 7.29e-125: 357: 99.62		CDN1A_HUMAN (17-148): 7.59e-31: 115: 29.20
+	Xl
		1137615 Q6PF20_XENLA (1-261): 2.46e-122: 350: 89.66		Q5V9L9_XENLA (26-155): 9.15e-30: 112: 23.08
+	Xl
		1161302 Q6PF20_XENLA (1-261): 2.46e-122: 350: 89.66		Q91646_XENLA (26-155): 1.89e-17: 81.3: 28.46