Interactor 1: VEMP (P0DTC4)
Envelope small membrane protein (E) (sM protein)
Gene: E

Interactor 2: VEMP (P0DTC4)
Envelope small membrane protein (E) (sM protein)
Gene: E

Species: Severe acute respiratory syndrome coronavirus 2

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 32838362, 33845483, 35100873, 34672954, 36682677, 36219675, 36362071, 37483225, 39261533, 38467836, 39167680, 33177698
Identification Methods two hybrid, affinity chromatography technology, proximity labelling technology, x-ray crystallography, pull down, fluorescent resonance energy transfer, solid state nmr, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CoV_E~CoV_E
Common GO terms GO:0016020 - membrane
GO:0044178 - host cell Golgi membrane
GO:0046760 - viral budding from Golgi membrane
GO:0052025 - symbiont-mediated perturbation of host cell endomembrane system
GO:0055036 - virion membrane
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 75
Sa

1 75
+ Sa

Service provided by Combinatics, Japan

Last updated: 11Aug2025