Interactor 1: VME1 (P0DTC5)
Membrane protein (M) (E1 glycoprotein) (Matrix glycoprotein) (Membrane glycoprotein)
Gene: M

Interactor 2: VME1 (P0DTC5)
Membrane protein (M) (E1 glycoprotein) (Matrix glycoprotein) (Membrane glycoprotein)
Gene: M

Species: Severe acute respiratory syndrome coronavirus 2

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 32838362, 34709727, 35100873, 36264056, 34672954, 34671206, 37483225, 38467836, 888800001196, 38416838
Identification Methods affinity chromatography technology, proximity labelling technology, x-ray crystallography, biochemical, pull down, protein complementation assay, fluorescent resonance energy transfer, bimolecular fluorescence complementation, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CoV_M~CoV_M
Common GO terms GO:0005886 - plasma membrane
GO:0019031 - viral envelope
GO:0039545 - symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
GO:0039660 - structural constituent of virion
GO:0044178 - host cell Golgi membrane
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 222
Sa

1 222
+ Sa

Service provided by Combinatics, Japan

Last updated: 11Aug2025