Interactor 1: NS6 (P0DTC6)
ORF6 protein (ORF6) (Accessory protein 6) (Non-structural protein 6) (ns6) (Protein X3)
Gene: 6

Interactor 2: NS6 (P0DTC6)
ORF6 protein (ORF6) (Accessory protein 6) (Non-structural protein 6) (ns6) (Protein X3)
Gene: 6

Species: Severe acute respiratory syndrome coronavirus 2

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.748

The method score is based on:

Property Details
Experiments 33845483, 32838362, 34672954, 34781739, 38467836, 37218505, 39480836, 37707320
Identification Methods affinity chromatography technology, proximity labelling technology, two hybrid, fluorescent resonance energy transfer, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005643 - nuclear pore
GO:0016020 - membrane
GO:0039502 - symbiont-mediated suppression of host type I interferon-mediated signaling pathway
GO:0039548 - symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity
GO:0039563 - symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT1 activity
and 5 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 61
Sa

1 61
+ Sa

Service provided by Combinatics, Japan

Last updated: 11Aug2025