Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA

Interactor 2: CDK6 (Q00534)
Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)
Gene: CDK6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005813 - centrosome
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 261
Hs

1 326
+ Bt
+ Hs
+ Mm
+ Mm
+ Hs
+ Bt
+ Hs
+ Bt
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024