Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA

Interactor 2: DPOE1 (Q07864)
DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase II subunit A)
Gene: POLE

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.878

The method score is based on:

Property Details
Experiments 26903512, 12171929, 20227374, 24958773
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_pol_B~PCNA_N
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006272 - leading strand elongation
GO:0006287 - base-excision repair, gap-filling
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 261
Hs

1 2286
+ Dm
+ Hs
+ Mm
+ At
+ Dm
+ Sp
+ Sc
+ Sc
+ Ss

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024